The conjunction 致使 connects parts of a complex sentence.
致使 is followed by the result of a situation that was described in the first part of a sentence. This result is often negative.
Scheme
situation
致使
result
Examples
他的父亲遭受严重过敏反应,致使心跳停止
His father had a severe allergic reaction that caused his heart to stop
tā de fùqin zāoshòu yánzhòng guòmǐn fǎnyìng, zhìshǐ xīntiào tíngzhǐ
由于地址字迹不清,致使信件无法投递
Mail was not delivered because the address was illegible